Safety and pharmacokinetics of intrathecal administration of pemetrexed in rats

作者: Jong-Mu Sun , Mi Hyun Nam , Jae Yong Chung , Bohee Im , Soo-Youn Lee

DOI: 10.1007/S00280-010-1522-7

关键词:

摘要: Purpose Leptomeningeal carcinomatosis is a devastating complication of malignant disease. In this study, we evaluated the safety and pharmacokinetics intrathecally administered pemetrexed in rats.

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