作者: Jong-Mu Sun , Mi Hyun Nam , Jae Yong Chung , Bohee Im , Soo-Youn Lee
DOI: 10.1007/S00280-010-1522-7
关键词:
摘要: Purpose Leptomeningeal carcinomatosis is a devastating complication of malignant disease. In this study, we evaluated the safety and pharmacokinetics intrathecally administered pemetrexed in rats.