The renaissance of aminoacyl‐tRNA synthesis

作者: Michael Ibba , Dieter Söll

DOI: 10.1093/EMBO-REPORTS/KVE095

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摘要: The role of tRNA as the adaptor in protein synthesis has held an enduring fascination for molecular biologists. Over four decades study, taking numerous milestones biology, led to what was widely be a fairly complete picture how tRNAs and amino acids are paired prior synthesis. However, recent developments genomics structural biology have revealed unexpected array new enzymes, pathways mechanisms involved aminoacyl-tRNA As more now begins emerge, high degree evolutionary diversity this universal essential process is becoming clearer.

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