Prophylactic or therapeutic agent for optic nerve disorders comprising 4,6-dichloro-1h-indole-2-carboxylic acid derivative or salt thereof as active ingredient
作者： Masaaki Kageyama , Hisayuki Seike , Masaaki Sasaoka , Tomoko Umemoto
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摘要: Disclosed is a compound useful as prophylactic or therapeutic agent for optic nerve disorders, an inhibitor of retinal ganglion cell death restoring the expression level neurofilament light chain, particularly capable exhibiting above-mentioned pharmacological activities when administered orally. A 4,6-dichloro-1H-indole-2-carboxylic acid derivative salt thereof can significantly inhibit decrease in number cells layer NMDA-induced rat disorder model to orally, and also restore chain retina intravitreally (intraocular local administration). Therefore, chain.
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