Indole derivatives and pharmaceutical use thereof

作者: Alfredo Cugola , Giovanni Gaviraghi

DOI:

关键词:

摘要: The invention relates to the compound of formula (I) ##STR1## wherein A represents an unsubstituted ethenyl group in trans (E) configuration or a physiologically acceptable salt metabilically labile ester thereof which are antagonists excitatory amino acids, processes for their preparation and use medicine.

参考文章(5)
Alex A. Cordi, William F. Hood, Brian K. Cheng, Nancy M. Gray, Michael S. Dappen, Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders ,(1992)
Bruce M. Baron, Boyd L. Harrison, Excitatory amino acid antagonists ,(1990)
Graham Johnson, Po-Wai Yuen, Christopher Franklin Bigge, Novel derivatives of 2-carboxyndoles having pharmaceutical activity ,(1992)
Graham Johnson, Thomas C. Malone, Po-Wai Yuen, Substituted 2-carboxylindoles having pharmaceutical activity ,(1991)