Lithium as a Differential Neuroprotector During Brain Irradiation

摘要: Radiotherapy remains a major treatment modality for primary and metastatic brain tumors, as well leukemia lymphoma involving the central nervous system (CNS). Cranial irradiation is also used prophylaxis patients at high risk of involvement by neoplasia, example small-cell lung cancer. Despite important advances in diagnosis therapy malignant solid metastases continue to present significant problems clinicians attempting prevent progression disease limit morbidity associated with therapy. Indeed, up two thirds all cause clinical symptoms [1, 2]. In addition, there evidence that overall incidence increasing because improved systemic cancer [3]. Further, survival rates children both [4, 5, 6, 7], secondary [3] tumors are increasing.