Naegleria gruberi metabolism.

摘要: The completion of the genome project for Naegleria gruberi provides a unique insight into metabolic capacities an organism, which there is almost complete lack experimental data. metabolism seems to be extremely versatile, as can expected free-living amoeboflagellate, but although considered fully aerobic, its also predicts important anaerobic traits. Other predictions are that carbohydrates oxidised carbon dioxide and water when oxygen not limiting in absence end-products will succinate, acetate minor quantities ethanol D-lactate. hybrid mitochondrion/hydrogenosome has both cytochromes [Fe] hydrogenase, pyruvate-ferredoxin oxidoreductase. Genomic information possibility identify drugs with possible mode action fatal primary amoebic meningoencephalitis caused by closely related opportunistic pathogen fowleri.