The use of superparamagnetic nanoparticles for prosthetic biofilm prevention
作者： Thomas J Webster
DOI: 10.2147/IJN.S5976
关键词:
摘要: As with all surgical procedures, implantation comes the added risk of infection. The goal this in vitro study was to explore use superparamagnetic iron oxide nanoparticles (SPION) as a multifunctional platform prevent biofilm formation. Results showed for first time decreased Staphylococcus epidermidis numbers when exposed 100 microg/ml SPION 12 hours and trend continued up 48 hours. Prevention colony assembly, prerequisite formation, also observed at lower dosages 10 after Coupled previous studies demonstrating enhanced bone cell functions presence same concentration SPION, present results provided much promise numerous anti-infection orthopedic applications.
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