Development of Type I Gastric Carcinoid in patients with Chronic atrophic gastritis

作者: L. Vannella , A. Sbrozzi-Vanni , E. Lahner , C. Bordi , E. Pilozzi

DOI: 10.1111/J.1365-2036.2011.04659.X

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摘要: Summary Background  Long-term observational studies assessing the incidence of type I gastric carcinoid (typeIGC) in patients with chronic atrophic gastritis are few. Aim  To evaluate occurrence typeIGC at diagnosis and during follow-up to identify patient features associated presence a cohort patients. Methods  Three hundred sixty-seven [245 women, age 54 (18–79) years] underwent regular by gastroscopy. The was determined least 2 years (n = 214). Baseline clinical histological were analysed as factors univariate analysis. Results  Type diagnosed nine (2.4%) moment when diagnosed. After 1463 person-years, six developed an annual rate (person-year) 0.4%. Patients had significantly higher levels gastrin, chromogranin A more frequently body polyps ECL-dysplasia compared without typeIGC. Conclusions  This study shows that is rare complication gastritis, gastroscopic/histologic evaluation strongly typeIGC.

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