NO points to epigenetics in vascular development
作者： B. Illi , C. Colussi , J. Rosati , F. Spallotta , S. Nanni
DOI: 10.1093/CVR/CVR056
关键词:
摘要: Our understanding of epigenetic mechanisms important for embryonic vascular development and cardiovascular differentiation is still in its infancy. Although molecular analyses, including massive genome sequencing and/or vitro/in vivo targeting specific gene sets, has led to the identification multiple factors involved stemness maintenance or early processes layers specification, very little known about commitment lineages. The object this review will be outline state art field trace perspective therapeutic consequences studies aimed at elucidating fundamental networks. Special attention paid emerging role nitric oxide field.
oup.com
core.ac.uk
elsevier.com
oxfordjournals.org
sci-hub.se 参考文章(149)
Kevin V Morris, Barbora Malecová, Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs. Current Opinion in Molecular Therapeutics. ,vol. 12, pp. 214- 222 ,(2010)
Helle F. Jørgensen, Sara Giadrossi, Miguel Casanova, Mitsuhiro Endoh, Haruhiko Koseki, Neil Brockdorff, Amanda G. Fisher, Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells. Cell Cycle. ,vol. 5, pp. 1411- 1414 ,(2006) , 10.4161/CC.5.13.2927
Q C Yang, C X Yang, Y M Lv, B F Zeng, Y W Liu, Y Dong, Z M Jiang, Z M Shi, J Huang, Inhibition of hypoxia-induced angiogenesis by trichostatin A via suppression of HIF-1a activity in human osteosarcoma. Journal of Experimental & Clinical Cancer Research. ,vol. 25, pp. 593- 599 ,(2006)
Aaron M. Zorn, James M. Wells, Molecular Basis of Vertebrate Endoderm Development International Review of Cytology-a Survey of Cell Biology. ,vol. 259, pp. 49- 111 ,(2007) , 10.1016/S0074-7696(06)59002-3
Fernando G. Osorio, Ignacio Varela, Ester Lara, Xose S. Puente, Jesús Espada, Raffaella Santoro, José M. P. Freije, Mario F. Fraga, Carlos López-Otín, Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease Aging Cell. ,vol. 9, pp. 947- 957 ,(2010) , 10.1111/J.1474-9726.2010.00621.X
Gary K. Owens, Molecular Control of Vascular Smooth Muscle Cell Differentiation and Phenotypic Plasticity Vascular Development. ,vol. 283, pp. 174- 193 ,(2007) , 10.1002/9780470319413.CH14
Osamu Ohneda, Masumi Nagano, Yoshiaki Fujii‐Kuriyama, Role of hypoxia-inducible factor-2alpha in endothelial development and hematopoiesis. Methods in Enzymology. ,vol. 435, pp. 199- 218 ,(2007) , 10.1016/S0076-6879(07)35011-8
Myoung Sook Kim, Ho Jeong Kwon, You Mie Lee, Jin Hyen Baek, Jae-Eun Jang, Sae-Won Lee, Eun-Joung Moon, Hae-Sun Kim, Seok-Ki Lee, Hae Young Chung, Chul Woo Kim, Kyu-Won Kim, Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nature Medicine. ,vol. 7, pp. 437- 443 ,(2001) , 10.1038/86507
Masanori Hirashima, Hiroshi Kataoka, Satomi Nishikawa, Norihisa Matsuyoshi, Shin-Ichi Nishikawa, Maturation of Embryonic Stem Cells Into Endothelial Cells in an In Vitro Model of Vasculogenesis Blood. ,vol. 93, pp. 1253- 1263 ,(1999) , 10.1182/BLOOD.V93.4.1253
Claudia Colussi, Chiara Mozzetta, Aymone Gurtner, Barbara Illi, Jessica Rosati, Stefania Straino, Gianluca Ragone, Mario Pescatori, Germana Zaccagnini, Annalisa Antonini, Giulia Minetti, Fabio Martelli, Giulia Piaggio, Paola Gallinari, Christian Steinkuhler, Emilio Clementi, Carmela Dell'Aversana, Lucia Altucci, Antonello Mai, Maurizio C Capogrossi, Pier Lorenzo Puri, Carlo Gaetano, HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 19183- 19187 ,(2008) , 10.1073/PNAS.0805514105