Oral contraceptive use and liver cancer.

摘要: The risk of liver cancer in relation to the use oral contraceptives was evaluated a hospital-based case-control study conducted 5 US cities between 1977-85. 12 new cases were identified women ages 19-54; controls selected from among patients hospitalized for acute conditions unrealted contraceptive (OC) matched each case on age (5-year categories) date interview (3- year and geographic location hospital. Among 9 classified as having hepatocellular carcinoma 8 (89%) had used OCs; only 16 (36%) 45 OCs. 3 other (2 with cholangiocarcinomas 1 undetermined type) all OCs compared 4 15 controls. results confirm strong positive association OC observed earlier studies. Such an is consistent evidence that associated benign hepatic tumors young women. However number attributable probably small because extremely rare US. (authors)