Fine-needle aspiration cytology of a mediastinal seminoma associated with multilocular thymic cyst.

作者: Jan F. Silverman , Peter R. Olson , David J. Dabbs , Rodney Landreneau

DOI: 10.1002/(SICI)1097-0339(199904)20:4<224::AID-DC8>3.0.CO;2-C

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摘要: Multiloculated thymic cysts are uncommon lesions that can be either acquired or associated with malignancies. This report describes the fine-needle aspiration (FNA) cytology of a mediastinal seminoma prominent cystic change, confirmed by surgical pathology examination and ancillary studies performed on both tissue specimens. The FNA revealed clusters malignant oval-to-polygonal-shaped cells large oval nuclei possessing nucleoli set in pale-to-eosinophilic cytoplasm. These were surrounded dense lymphoid infiltrate along few noncaseating granulomas. stained positive for placental alkaline phosphatase (PLAP) negative low molecular broad-spectrum cytokeratin. differential diagnosis malignancies is presented. To best our knowledge, this first multilocular cyst.

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