Age-Related Cognitive Decline in the Rhesus Monkey

摘要: It is only in the last 25 years that significant strides have been taken toward development of primate models normal human aging. Together with advances fields molecular biology, neuroimaging, and behavioral neuroscience, these emerged as potentially important components our understanding age-related cognitive decline humans (Peters et al., 1996). This not to say studies using other species, particularly rodents, provided a wealth information on neurobiological substrates However, rich repertoire monkey, monkey’s remarkable ability perform variety complex short-term memory tasks, many administered geriatric research studies, has made this species suited assess function at level possible nonprimates.