Clotting factor IX levels in C/EBPα knockout mice

作者: N. Davies , D. E. G. Austen , M. D. Wilde , G. J. Darlington , G. G. Brownlee

DOI: 10.1046/J.1365-2141.1997.4603263.X

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摘要: Previous studies have indicated that C/EBPα is involved in the regulation of factor IX and mutations a C/EBP recognition element promoter result haemophilia B. We now report mice homozygous for deletion c/ebpα gene are significantly deficient transcription.

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