Case with triple-negative breast cancer shows overexpression of both cFOS and TGF-β1 in node-positive tissue.
作者： Vesna Ivanović , Nasta Dedović-Tanić , Zorka Milovanović , Silvana Lukić , Srdjan Nikolić
关键词:
摘要: We present herein a case report style article on rare advanced triple-negative breast cancer (TNBC) patient with 6-month disease-free interval, and 10-month overall survival. Our results demonstrate that the poor clinical outcome of this was associated pronounced, more than fivefold higher, overexpression both cFOS TGF-β1 proteins in its metastatic nodal tissue extracts, when compared values two non-TNBC controls (with ‘zero’ interval survival). This original observation suggests, for first time, may be considered as pair biomarkers an early assessment prognosis TNBC patients. The possible implication is discussed.
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