Metastatic eccrine porocarcinoma: Response to docetaxel (Taxotere) chemotherapy

作者: T.A. Plunkett , A.M. Hanby , D.W. Miles , R.D. Rubens

DOI: 10.1023/A:1011196615177

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摘要: Summary Background Eccrine porocarcinoma is an uncommon neoplasm of the intra-epidermal sweat gland duct. Patients and methods A case eccrine in a female renal transplant patient aged 45 years described with review pertinent literature. Results The primary tumour was highly pleomorphic. In places large small cells merged focally former component infiltrated epidermis manner akin to Paget’s disease breast. majority high grade; using modified Bloom Richardson grading system, usually applied mammary ductal carcinomas, graded as 3. Metastatic developed nine months following surgical treatment. metastatic resistant epirubicin but responded docetaxel chemotherapy. Conclusions There are no data support use adjuvant therapy management porocarcinoma. system may define cases at risk relapse which might be considered. has proven many chemotherapeulic agents. We report first this disease. treatment well tolerated resulted marked symptomatic radiological responses. Treatment should considered future rare tumour.

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