Lactate Dehydrogenase-B Is Silenced by Promoter Methylation in a High Frequency of Human Breast Cancers
作者： Nicola J. Brown , Sue E. Higham , Branko Perunovic , Mohammad Arafa , Sabapathy Balasubramanian
DOI: 10.1371/JOURNAL.PONE.0057697
关键词:
摘要: Objective Under normoxia, non-malignant cells rely on oxidative phosphorylation for their ATP production, whereas cancer Glycolysis; a phenomenon known as the Warburg effect. We aimed to elucidate mechanisms contributing effect in human breast cancer.
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