Influence of tea drinking on manganese intake, manganese status and leucocyte expression of MnSOD and cytosolic aminopeptidase P.

摘要: Since black tea contains high levels of manganese (Mn), we investigated the relationship between dietary Mn intake, circulating and leucocyte expression two Mn-dependent enzymes in drinkers non-tea drinkers. We assessed intakes (food frequency questionnaire), fasting whole blood plasma levels, quantitative peripheral mononuclear cell superoxide dismutase (MnSOD) cytosolic aminopeptidase-P (cAP-P). In total, 24 (⩾1 l tea/day) 28 were recruited from staff students King's College London by circular email. Dietary (mean (range)) significantly lower (P<0.0001) non (3.2 mg/day (0.5–6.5)) than (5.5 mg/day (2–12) or 10 mg/day (5–20) depending upon value used for tea). Whole blood, MnSOD cAP-P did not differ groups. a continuous analysis, correlated inversely but no other parameters associated with each other. Tea drinking is major source commonly exceed proposed adequate intake values 1.8–2.3 mg Mn/day and, on occasion, upper limits 10–11 mg/day. has little influence markers status enzymes. Fasting could, together, be further as status. S-JH was supported through EPSRC PTP scheme. Running costs UK Technical Trade Association.