Carbocation scavenging during oligonucleotide synthesis

作者: Dennis Mulvey , Vasulinga Ravikumar , Douglas L. Cole , Mark Andrade

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摘要: During the synthesis of oligonucleotides and phosphate linked oligomers, a carbocation scavenging agent is employed to increase overall yield. The used in conjunction with an acidic solution during deprotection step.

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