Advances in the Synthesis of Oligonucleotides by the Phosphoramidite Approach
作者： Serge L. Beaucage , Radhakrishman P. Iyer
DOI: 10.1016/S0040-4020(01)88752-4
关键词: Phosphoramidite 、 Chemistry 、 Combinatorial chemistry 、 Oligonucleotide
摘要: … 5’)~ intemucleotidic linkage identical to natural DNA. Their pioneering approach was based on … 3 was converted, upon removal of the protecting groups, to the natural thymidylic acid 4. …
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