Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives

作者： Richard T. Pon , Nassim Usman , Masad J. Damha , Kelvin K. Ogilvie

关键词:

摘要: Phosphoramidite reagents can phosphitylate guanine bases at the O 6 -position during solid phase synthesis and serious chain cleavage occurs if the base phosphitylation is not …

参考文章(0)

Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives

来源期刊

我的账户

Prevention of guanine modification and chain cleavage during the solid phase synthesis of oligonucleotides using phosphoramidite derivatives

来源期刊

相似文章 10

我的账户