A facile synthesis of 5'-end solid-anchored, 3'-end free oligodeoxyribonucleotides via the (5'-->3')-elongated phosphoramidite strategy.
作者： Akira Sakakura , Yoshihiro Hayakawa
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摘要: It is demonstrated that not only N2- but also O6-protection of the guanine base necessary for obtaining oligodeoxyribonucleotides in high yields and at a purity solid-phase synthesis via (5'--> 3')-chain elongated phosphoramidite approach.
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