Device for dispensing drug by combined diffusional and osmotic operations

作者: Felix Theeuwes

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摘要: A device is disclosed for delivering an agent to environment of use at a substantially constant rate over time. The comprises wall formed microporous material surrounding compartment housing the and thermodynamic member. member film expandable, semipermeable means expanding can occupy any space-position in compartment, it also be contact with wall. In operation, when environment, delivered from by diffusion through fluid-filled paths wall, external fluid simultaneously entering paths, also, imbibed present or directly across causing expand, fill continuously maintain saturated state thereby zero order release prolonged period