Osmotic system for delivering selected beneficial agents having varying degrees of solubility
作者： Felix Theeuwes
DOI:
关键词:
摘要: An osmotic system for delivering an agent is disclosed. The comprises a wall surrounding compartment and has passageway through the from compartment. formed of material permeable to passage external fluid impermeable agent. contains that soluble in exhibits pressure gradient across against fluid, or limited solubility fluid. also suspending delivery member increasing amount delivered system. semipermeable film osmotically effective compound it able increase volume over time. In operation, at controlled rate by being imbibed into produce solution suspension containing agent, urging fill compartment, whereby released permeability wall, prolonged period
lens.org 参考文章(13)
R Ness, Microporous ocular device ,(1971)
Richard William Baker, Controlled release delivery system by an osmotic bursting mechanism ,(1975)
Felix Theeuwes, Osmotic dispenser with gas generating means ,(1975)
Jr George Milosovich, Controlled release dosage form containing water-swellable beadlet ,(1962)
Felix Theeuwes, Alan S. Michaels, Alejandro Zaffaroni, Osmotic releasing device having a plurality of release rate patterns ,(1977)
Alejandro Zaffaroni, Novel drug delivery device ,(1975)
Felix Theeuwes, Atul D. Ayer, Laminated osmotic system for dispensing beneficial agent ,(1976)
F Theeuwes, Osmotically powered agent dispensing device with filling means ,(1971)
Higuchi T, Osmotic dispenser with collapsible supply container ,(1971)
Felix Theeuwes, Atul D. Ayer, Osmotically driven active agent dispenser ,(1979)