The rebel angel: mutant p53 as the driving oncogene in breast cancer
作者： D. Walerych , M. Napoli , L. Collavin , G. Del Sal
关键词:
摘要: Breast cancer is the most frequent invasive tumor diagnosed in women, causing over 400 000 deaths yearly worldwide. Like other tumors, it is a disease with a complex, heterogeneous …
oup.com
units.it
oxfordjournals.org
core.ac.uk 参考文章(171)
Toretsky J, Blagosklonny Mv, Neckers L, Geldanamycin selectively destabilizes and conformationally alters mutated p53. Oncogene. ,vol. 11, pp. 933- 939 ,(1995)
Hiroko Yamashita, Mariko Nishio, Tatsuya Toyama, Hiroshi Sugiura, Zhenhuan Zhang, Shunzo Kobayashi, Hirotaka Iwase, Coexistence of HER2 over-expression and p53 protein accumulation is a strong prognostic molecular marker in breast cancer Breast Cancer Research. ,vol. 6, pp. 1- 7 ,(2003) , 10.1186/BCR738
Dominic A. Scudiero, Kurt W. Kohn, John N. Weinstein, Stephen Friend, Joany Jackman, Albert J. Fornace, Timothy G. Myers, Masato Mutoh, Edward A. Sausville, Saijun Fan, Ann Monks, Patrick M. O'Connor, Insoo Bae, Characterization of the p53 Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents Cancer Research. ,vol. 57, pp. 4285- 4300 ,(1997)
Elena Martynova, Silvia Pozzi, Valentina Basile, Diletta Dolfini, Federico Zambelli, Carol Imbriano, Giulio Pavesi, Roberto Mantovani, Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63 Oncotarget. ,vol. 3, pp. 132- 143 ,(2012) , 10.18632/ONCOTARGET.447
Nancy Hamel, Marc S. Greenblatt, Jeffrey P. Bond, William D. Foulkes, Pierre O. Chappuis, TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution. Cancer Research. ,vol. 61, pp. 4092- 4097 ,(2001)
Damian J. Junk, Lukas Vrba, George S. Watts, Marc M. Oshiro, Jesse D. Martinez, Bernard W. Futscher, Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia. ,vol. 10, pp. 450- 461 ,(2008) , 10.1593/NEO.08120
W Kolch, D Marmé, G Brandner, H A Weich, A Kieser, Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene. ,vol. 9, pp. 963- 969 ,(1994)
James G. Jackson, Vinod Pant, Qin Li, Leslie L. Chang, Alfonso Quintás-Cardama, Daniel Garza, Omid Tavana, Peirong Yang, Taghi Manshouri, Yi Li, Adel K. El-Naggar, Guillermina Lozano, p53-Mediated Senescence Impairs the Apoptotic Response to Chemotherapy and Clinical Outcome in Breast Cancer Cancer Cell. ,vol. 21, pp. 793- 806 ,(2012) , 10.1016/J.CCR.2012.04.027
Wan Mui Chan, Wai Yi Siu, Anita Lau, Randy Y. C. Poon, How Many Mutant p53 Molecules Are Needed To Inactivate a Tetramer Molecular and Cellular Biology. ,vol. 24, pp. 3536- 3551 ,(2004) , 10.1128/MCB.24.8.3536-3551.2004
Vessela Nedelcheva Kristensen, Tone Ikdahl Andersen, Bjorn Krikstein, Gry Geitvik, Eva Skovlund, Jahn M. Nesland, Anne-Lise Borresen-Dale, Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status and clinicopathological variables in breast cancer patients. Pharmacogenetics. ,vol. 8, pp. 441- 447 ,(1998) , 10.1097/00008571-199810000-00009