FIXATION CHANGES AFTER FRONTAL EYE-FIELD LESIONS IN MONKEYS

摘要: Abstract Rhesus monkeys were trained to look through a peep-hole and fixate 2° mirror which showed reflexion of their own eye. Their direction gaze was determined the nearest 3.5° using corneal photography, accuracy with they fixated plotted pre- post-operatively. Unilateral frontal eye-field lesions produced consistent, though usually transient, shift in fixation up 10° ipsilateral side. On recovery, removal second larger (up 20°) longer lasting opposite direction. Both unilateral one-stage bilateral also downward 25°, monkey's eyes tending toward primary, straight-ahead position. These changes persisted after there no oculomotor change evident on gross observation, worst case recovery over 4 months testing. Additional superior colliculus, or lesion sulcus principalis, had effect fixation. suggest that eye-fields normally exert at least tonic influence eye muscle nuclei.