Timolol: a 4-year follow-up study.

摘要: In 25 patients with ocular hypertension and open angles timolol maleate lowered the intraocular pressure (IOP) of 71% 49 eyes treated, keeping it below 22 mm Hg during 4 years therapy. However, IOP tended to drift upward by 2 per year, especially first third follow-up periods (1 year long respectively). Thus, should be examined every 3 months after an adequate response therapy is achieved. this series there was a slight visual loss in about 38% patients, but probably related increasing age. Field occurred four spite good Increased cupping optic disc six whom had pretreatment 30 or greater. Timolol well tolerated being virtually symptom-free. special care would needed treating asthma, bradycardia congestive heart failure.