Pharmacogenetics of timolol

摘要: In recent years, β-adrenergic blockers have become the first choice drugs for glaucoma treatment. Timolol holds main position among them, being a part of most combined antiglaucoma preparations. The use timolol maleate in clinical practice may be accompanied by severe side effects affecting different organs and systems. fact that cells with receptors are widely common within human body explains pharmacodynamic maleate. Because these undesirable effects, often evokes negative reaction from doctors patients, which to certain extent limits its usage ophthalmological practice. Obviously, efficacy safety administration depends on individual characteristics making personalized approach necessary every patient. Such particular approach, foundation medicine, increases while reducing costs using targeted doses.