Can mesenchymal cells undergo collective cell migration? The case of the neural crest

摘要: Cell migration is critical for proper development of the embryo and also used by many cell types to perform their physiological function. For instance, essential immune cells monitor body epithelial heal a wound whereas, in cancer cells, acquisition migratory capabilities step towards malignancy. Migratory are often categorized into two groups: mesenchymal produced an epithelium-to-mesenchyme transition, that undergo solitary epithelial-like which migrate collectively. However, on some occasions, may travel large, dense groups exhibit key features collectively migrating such as coordination cooperation. Here, using data published Neural Crest highly invasive population extensively throughout embryo, we explore idea other including might be able collective ...