Malignant peritoneal mesothelioma

摘要: Background and Objectives The incidence of malignant peritoneal mesothelioma (MPM) is rising. Our aim was to present our experience with this entity in order increase the awareness about disease avoid misdiagnosis. Methods Records seven patients histologically confirmed MPM were retrospectively reviewed. Demographic clinicopathological findings studied detail. Results There two females 5 males; mean age 50.3 years (range 16–73). Asbestos exposure recorded patients, familial Mediterranean fever one previous radiation one. Main presentations abdominal pain distension. None diagnosed preoperatively. The average delay diagnosis 10 months. Calretinin expression identified all tumors. Three treated cytoreductive surgery combined systemic chemotherapy. Two who remain alive young female by laparoscopic incidental hyperthermic intraoperative intraperitoneal chemotherapy (HIIC). Median survival 19.7 time five died their diseases 10.2 months. Conclusions An important prevent misdiagnosis. Immunohistochemistry has an role confirming diagnosis. remains a difficult therapeutic challenge. Thorough cornerstone current treatment while HIIC promising strategy suitable patients. J. Surg. Oncol. 2005;91:17–25. © 2005 Wiley-Liss, Inc.