Is prefrontal cortex involved in cued recall? A neuropsychological test of PET findings.

摘要: Positron emission tomography (PET) experiments have detected blood flow activations in right anterior prefrontal cortex during performance of a word stem cued recall task [3, 38]. Based on findings from variety PET studies, the "hemispheric encoding/retrieval asymmetry model" [44] was proposed to explain role frontal lobes episodic memory. This model asserts that left is preferentially involved encoding new information into memory, whereas more memory retrieval. As neuropsychological test this hypothesis, group patients with lesions areas 6, 8, 9, 10, 44, 45 and/or 46 (11 left, five right) were run under two semantic study conditions. group, these not significantly impaired recall. In first but second experiment, recalled fewer words than controls. Right either list. could be activated by several strategic aspects paradigm minimized present experiment. Brain reorganization lesioned also account for their intact performance. The regions studies young controls are necessary perform task.