作者: Jean-Pierre Guengant , Jacques Bangou , Batya Elul , Charlotte Ellertson
DOI: 10.1016/S0010-7824(99)00074-8
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摘要: Abstract Mifepristone-misoprostol medical abortion promises to revolutionize reproductive health-care. Several simplifications of the standard three clinic visit regimen may be possible, however. Particularly in developing countries, access method can greatly increased by eliminating longest visit. Indeed, shortly after mifepristone’s introduction Guadeloupe, a semi-developed Caribbean territory administered France, 1991, two authors conducted small prospective study one treatment-visit regimen. The was subsequently adopted as care for on island. Women (n = 92) with amenorrhea ≤49 days received 600 mg mifepristone under clinical supervision and were given 400 μg oral misoprostol home administration 2 later, returning weeks later follow-up. success rate (95.4%) is comparable rates found when both drugs are from similar recently United States. Adverse events also protocols requiring in-clinic misoprostol. Protocol adherence appeared excellent loss follow-up rare. We suggest that safe effective most nonindustrialized settings.