Abortion induced with methotrexate and misoprostol

摘要: OBJECTIVE: To determine the outcome and side effects of a new drug protocol to induce abortion. DESIGN: Case series. SETTING: An urban primary care practice. PATIENTS: One hundred consecutive patients who requested elective termination pregnancies less than 8 weeks9 gestation. INTERVENTION: Subjects received methotrexate (50 mg/m2 body surface area, administered intramuscularly) and, 3 days afterward, misoprostol (800 micrograms, given vaginally). OUTCOME MEASURES: Number abortions induced within 24 hours 10 administration, number surgical aspirations conducted because incomplete abortion, mean amount bleeding pain women who, if faced with same situation, said they would again choose drug-induced abortion over one. RESULTS: Abortion occurred administration among 48 69 women. In total, 89 had an without aspiration. Of these women, 71 choice again. CONCLUSION: appears be feasible alternative deserves further study.