作者: Jeffrey T Jensen , Susan J Astley , Elizabeth Morgan , Mark D Nichols
DOI: 10.1016/S0010-7824(99)00016-5
关键词: Medicine 、 Obstetrics 、 Medical abortion 、 Misoprostol 、 Vacuum Curettage 、 Surgery 、 Curettage 、 Abortifacient 、 Incomplete Abortion 、 Vacuum aspiration 、 Abortion
摘要: A prospective, nonconcurrent cohort analysis of 178 mifepristone/misoprostol and 199 suction curettage abortion subjects, ages > or = 18 years, with intrauterine pregnancies < 63 days estimated gestational age, was conducted to compare the outcomes those medical abortion. The subjects received 600 mg mifeprisone orally, followed by 400 micrograms oral misoprostol 2 later. Surgical underwent electronic vacuum aspiration. All were for weeks until absence clinical bleeding. Outcome measures included a successful (complete without surgical intervention), duration bleeding, morbidity. Overall, 18.3% 4.7% patients failed their primary procedure an unanticipated (RR 3.93, 95% CI 1.87, 8.29). Four mifepristone required acute nine manage ongoing pregnancy, five incomplete Fourteen eight persistent median time delay therapeutic significantly longer in group (35 versus 8 days; Mann-Whitney U 17.0, p 0.008). Medical experienced bleeding (mean difference 9.6 days, 6.8, 12.4). No significant change hemoglobin occurred either group. Mifepristone reported greater pain (77.1% vs 10.5%; RR 7.4, 4.7, 11.5), nausea vomiting (68.6% 0.6%; 117.9, 16.7, 834.7). Women receiving are more likely require unplanned intervention than women who undergo curettage. They experience discomfort follow-up interval, bleed period, remain at risk completion several weeks.