Towards elucidating the connection between epithelial-mesenchymal transitions and stemness.
作者： Mohit Kumar Jolly , Bin Huang , Mingyang Lu , Sendurai A. Mani , Herbert Levine
关键词:
摘要: Epithelial cells undergoing epithelial-to-mesenchymal transitions have often been shown to behave as cancer stem cells, but the precise molecular connection remains elusive. At the …
royalsocietypublishing.org
paperity.org参考文章(62)
L.J. Penn, M.W. Brooks, E.M. Laufer, H. Land, Negative autoregulation of c-myc transcription. The EMBO Journal. ,vol. 9, pp. 1113- 1121 ,(1990) , 10.1002/J.1460-2075.1990.TB08217.X
Olivera Stojadinovic, Harold Brem, Constantinos Vouthounis, Brian Lee, John Fallon, Michael Stallcup, Ankit Merchant, Robert D. Galiano, Marjana Tomic-Canic, Molecular pathogenesis of chronic wounds: The role of β-catenin and c-myc in the inhibition of epithelialization and wound healing American Journal of Pathology. ,vol. 167, pp. 59- 69 ,(2005) , 10.1016/S0002-9440(10)62953-7
Hitoshi Niwa, Jun-ichi Miyazaki, Austin G. Smith, Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nature Genetics. ,vol. 24, pp. 372- 376 ,(2000) , 10.1038/74199
F. Hayot, C. Jayaprakash, NF-kappaB oscillations and cell-to-cell variability. Journal of Theoretical Biology. ,vol. 240, pp. 583- 591 ,(2006) , 10.1016/J.JTBI.2005.10.018
R Y-J Huang, M K Wong, T Z Tan, K T Kuay, A H C Ng, V Y Chung, Y-S Chu, N Matsumura, H-C Lai, Y F Lee, W-J Sim, C Chai, E Pietschmann, S Mori, J J H Low, M Choolani, J P Thiery, An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530) Cell Death and Disease. ,vol. 4, ,(2013) , 10.1038/CDDIS.2013.442
Mingyang Lu, Mohit Kumar Jolly, Jose' Onuchic, Eshel Ben-Jacob, Toward Decoding the Principles of Cancer Metastasis Circuits Cancer Research. ,vol. 74, pp. 4574- 4587 ,(2014) , 10.1158/0008-5472.CAN-13-3367
Dejuan Kong, Sanjeev Banerjee, Aamir Ahmad, Yiwei Li, Zhiwei Wang, Seema Sethi, Fazlul H. Sarkar, Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells. PLOS ONE. ,vol. 5, ,(2010) , 10.1371/JOURNAL.PONE.0012445
Caihong Qiu, Yinghong Ma, Jianquan Wang, Shuping Peng, Yingqun Huang, Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells Nucleic Acids Research. ,vol. 38, pp. 1240- 1248 ,(2010) , 10.1093/NAR/GKP1071
Ronghui Li, Jialiang Liang, Su Ni, Ting Zhou, Xiaobing Qing, Huapeng Li, Wenzhi He, Jiekai Chen, Feng Li, Qiang Zhuang, Baoming Qin, Jianyong Xu, Wen Li, Jiayin Yang, Yi Gan, Dajiang Qin, Shipeng Feng, Hong Song, Dongshan Yang, Biliang Zhang, Lingwen Zeng, Liangxue Lai, Miguel Angel Esteban, Duanqing Pei, A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts Cell Stem Cell. ,vol. 7, pp. 51- 63 ,(2010) , 10.1016/J.STEM.2010.04.014
Diwakar R. Pattabiraman, Robert A. Weinberg, Tackling the cancer stem cells — what challenges do they pose? Nature Reviews Drug Discovery. ,vol. 13, pp. 497- 512 ,(2014) , 10.1038/NRD4253