The emergence of Clostridium difficile ribotypes 027 and 176 with a predominance of the Clostridium difficile ribotype 001 recognized in Slovakia following the European standardized Clostridium difficile infection surveillance of 2016.
作者： Elena Novakova , Maria Stefkovicova , Maria Garabasova Kopilec , Martin Novak , Nina Kotlebova
DOI: 10.1016/J.IJID.2019.10.038
关键词:
摘要: Abstract Aim To obtain standardized epidemiological data for Clostridium difficile infection (CDI) in Slovakia. Methods Between October and December 2016, 36 hospitals Slovakia used the European Centre Disease Prevention Control (ECDC) surveillance protocol. Results The overall mean CDI incidence density was 2.8 (95% confidence interval 1.9–3.9) cases per 10 000 patient-days. Of 332 cases, 273 (84.9%) were healthcare-associated, 45 (15.1%) community-associated, 14 (4.2%) of recurrent CDI. A complicated course reported 14.8% (n = 51). outcome available 95.5% (n = 317). 35 patients (11.1%) who died, 34 did so within 30 days after their diagnosis. 78 isolates obtained from 12 hospitals, 46 belonged to PCR ribotype 001 (59.0%; 11 hospitals) 23 176 (29.5%; six hospitals). total 73 (93.6%) showed reduced susceptibility moxifloxacin (ribotypes 176; p Conclusions These results show emergence C. ribotypes 027 with a predominance 2016. Given that an almost homogeneous detected isolates, this stresses importance reducing fluoroquinolone prescriptions Slovak healthcare settings.
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