Epidemiology of chronic disc degeneration and osteoarthritis of the lumbar spine in Britain and Japan: a comparative study.

摘要: Objective, To compare the prevalence of spinal osteoarthritis (OA ) in Britain and Japan. Methods. A total 206 ten 188 women living Hertfordshire, UK. a 100 Miyama, Japan, aged 60-79 years were studied. Participants completed lifestyle questionnaire, anteroposterior lateral radiographs thoracic lumbar spine obtained under standardized conditions. Each radiograph was graded for osteoarthritic changes according to overall Kellgren-Lawrence (K-L) score. Gradings also recorded separately disc narrowing osteophyte formation. Results. British subjects much more likely have as K-L grade 4 severity (p = 0.05 men, p < 0.001 women). ). displayed greater 0.08), but less severe osteophytosis 0.06) than their Japanese counterparts. 0.001) formation 0.001). On multiple regression analysis, higher body mass index (BMI) associated with excess risk population (OR 1.84, 95% CI 1.12-3.02), not population. Differences between countries persisted after allowing age BMI. suggesting that differences build could fully explain OA 2 countries. Conclusion. We found degenerative disease is common UK mountain village exist both degeneration