Environmentally Sustainable Synthesis of Catalytically-Active Silver Nanoparticles and Their Cytotoxic Effect on Human Keratinocytes

摘要: Eco-friendly synthesis of metal nanoparticles using plant extracts plays a vital role in green nanotechnology. In this paper, method for synthesizing silver (AgNPs) is described by treating ions with the aqueous bark extract Acanthopanax sessiliflorus at ambient temperature. The synthesized AgNPs were characterized UV–Vis spectrophotometry, X-ray diffractometry (XRD), Fourier transform infrared spectroscopy and transmission electron microscopy (TEM). formation was monitored spectrophotometer, which exhibited maximum absorption peak (λ max) 435 nm, also color change from light yellowish to yellowish-brown observed. Powder XRD analysis revealed fcc crystals, TEM roughly-spherical shaped an average diameter ~20 nm. Thermogravimetric showed two-step thermal decomposition AgNPs, majorly started 150 °C continued gradually until 700 °C. These found catalyze reduction p-nitroaniline p-phenylenediamine presence sodium borohydride (NaBH4). catalytic reaction followed pseudo-first order kinetics rate constant (k) 8.7 × 10−3 min−1. vitro cytotoxic assay dose-dependent toxicity these human keratinocytes higher concentrations. cost-effective, sustainable, compatible industrial biomedical applications.