Influence of low doses of deoxynivalenol applied per os on chosen indexes of immune response in swine.

作者: Gajecki M , Obremski K , Zwierzchowski W , Zielonka L

DOI:

关键词:

摘要: Deoxynivalenole is one of the more often present micotoxins in home produced feeds. The immunosuppressive action this xenobiotic on animal organism plays an important role among other symptoms intoxication when high doses micotoxin are applied. However, low likely to activate some adaptive mechanisms immune system, a fact confirmed investigations.

参考文章(9)
M K Janiak, Uklad odpornosciowy przewodu pokarmowego Medycyna Weterynaryjna. ,vol. 52, pp. 611- 614 ,(1996)
K. Wojcicka-Lorenowicz, K. Kostro, Z. Glinski, L. Krakowski, Immunologiczne i immunopatologiczne mechanizmy zapalenia Medycyna Weterynaryjna. ,vol. 56, pp. 479- 485 ,(2000)
Paul H. Black, Stress and the inflammatory response: a review of neurogenic inflammation. Brain Behavior and Immunity. ,vol. 16, pp. 622- 653 ,(2002) , 10.1016/S0889-1591(02)00021-1
Ewa Kontny, Maria ZiÓŁKowska, Alicja Ryżewska, Włodzimierz Maśliński, Protein kinase c-dependent pathway is critical for the production of pro-inflammatory cytokines (TNF-alpha, IL-1beta, IL-6). Cytokine. ,vol. 11, pp. 839- 848 ,(1999) , 10.1006/CYTO.1998.0496
J.I. Azconaolivera, Y. Ouyang, J. Murtha, F.S. Chu, J.J. Pestka, Induction of Cytokine mRNAs in Mice After Oral Exposure to the Trichothecene Vomitoxin (Deoxynivalenol): Relationship to Toxin Distribution and Protein Synthesis Inhibition Toxicology and Applied Pharmacology. ,vol. 133, pp. 109- 120 ,(1995) , 10.1006/TAAP.1995.1132
R. Greenhalgh, B.A. Blackwell, M.E. Savard, The NMR spectra of trichothecenes and related fungal metabolites Tetrahedron. ,vol. 45, pp. 2373- 2383 ,(1989) , 10.1016/S0040-4020(01)83437-2
E. R. CHAVEZ, J. A. RHEAUME, THE SIGNIFICANCE OF THE REDUCED FEED CONSUMPTION OBSERVED IN GROWING PIGS FED VOMITOXIN-CONTAMINATED DIETS Canadian Journal of Animal Science. ,vol. 66, pp. 277- 287 ,(1986) , 10.4141/CJAS86-028
Vladimír Betina, Structure-activity relationships among mycotoxins Chemico-Biological Interactions. ,vol. 71, pp. 105- 146 ,(1989) , 10.1016/0009-2797(89)90030-6
Jean-Charles Leblanc, Laure Malmauret, David Delobel, Philippe Verger, Simulation of the Exposure to Deoxynivalenol of French Consumers of Organic and Conventional Foodstuffs Regulatory Toxicology and Pharmacology. ,vol. 36, pp. 149- 154 ,(2002) , 10.1006/RTPH.2002.1584