Germinal Center Derived Lymphomas in Humans and Mice

摘要: Tumor cells represent the neoplastic counterparts of normal elements which have undergone a series irreversible genetic alterations. The end result is cell capable indefinite proliferation and escaping many or all physiological control mechanisms. In general, tend to maintain at least some morphological and/or phenotypic features characteristic from they derive. This also applies lymphomas. Accordingly, human lymphomas been classified in different categories subgroups based on morphology cells, their immunophenotype capability follow differentiation pathways recapitulate lymphoid structure seen tissues.