Multi-Lineage Interrogation of the Performance Characteristics of a Split-Signal Fluorescence In Situ Hybridization Probe for Anaplastic Lymphoma Kinase Gene Rearrangements A Study of 101 Cases Characterized by Immunohistomorphology on Fixed Archival Tissue

作者: Leonard Hwan Cheong Tan , Elaine Do , Soo Yong Tan , Siew Meng Chong , Evelyn Siew Chuan Koay

DOI: 10.1007/BF03260066

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摘要: Background: Fluorescence in situ hybridization (FISH) can identify chromosomal translocations on fixed archival tissue, but studies cross-validating the utility of FISH lesions different cell lineages that harbor similar (e.g. those involving anaplastic lymphoma kinase [ALK]) have not been published.

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