Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma.
作者： Hong Zheng , Wei Dai , Arthur Kwok Leung Cheung , Josephine Mun Yee Ko , Rebecca Kan
关键词:
摘要: Nasopharyngeal carcinoma (NPC) is an epithelial malignancy with a unique geographical distribution. The genomic abnormalities leading to NPC pathogenesis remain unclear. In total, …
hku.hk
core.ac.uk 
sci-hub.se 参考文章(49)
Gary Chien, Po Wing Yuen, Dora Kwong, Yok Lam Kwong, Comparative genomic hybridization analysis of nasopharygeal carcinoma: Cancer Genetics and Cytogenetics. ,vol. 126, pp. 63- 67 ,(2001) , 10.1016/S0165-4608(00)00392-7
Hirokazu Noshiro, Masazumi Tsuneyoshi, Takeharu Yamanaka, Kentaro Hashizume, Masao Tanaka, Kenjiro Nakamura, Takashi Yao, Akihiko Uchiyama, Takashi Morisaki, Mitsuo Katano, Nobuhiko Sasaki, Nuclear Factor-κB p65 (RelA) Transcription Factor Is Constitutively Activated in Human Gastric Carcinoma Tissue Clinical Cancer Research. ,vol. 7, pp. 4136- 4142 ,(2001)
Charles Swanton, Nicholas McGranahan, Gabriel J. Starrett, Reuben S. Harris, APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity Cancer Discovery. ,vol. 5, pp. 704- 712 ,(2015) , 10.1158/2159-8290.CD-15-0344
Geraldine A. Auwera, Mauricio O. Carneiro, Christopher Hartl, Ryan Poplin, Guillermo del Angel, Ami Levy‐Moonshine, Tadeusz Jordan, Khalid Shakir, David Roazen, Joel Thibault, Eric Banks, Kiran V. Garimella, David Altshuler, Stacey Gabriel, Mark A. DePristo, From FastQ Data to High‐Confidence Variant Calls: The Genome Analysis Toolkit Best Practices Pipeline Current protocols in human genetics. ,vol. 43, ,(2013) , 10.1002/0471250953.BI1110S43
Mark M. Sasaki, Andrew D. Skol, Riyue Bao, Lindsay V. Rhodes, Rachelle Chambers, Everett E. Vokes, Ezra E.W. Cohen, Kenan Onel, Integrated Genomic Analysis Suggests MLL3 is a Novel Candidate Susceptibility Gene for Familial Nasopharyngeal Carcinoma Cancer Epidemiology, Biomarkers & Prevention. ,vol. 24, pp. 1222- 1228 ,(2015) , 10.1158/1055-9965.EPI-15-0275
Rebecca Kan, Wai Ho Shuen, Hong Lok Lung, Arthur Kwok Leung Cheung, Wei Dai, Dora Lai-Wan Kwong, Wai Tong Ng, Anne Wing Mui Lee, Chun Chung Yau, Roger Kai Cheong Ngan, Stewart Yuk Tung, Maria Li Lung, NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells PLOS ONE. ,vol. 10, pp. e0127239- ,(2015) , 10.1371/JOURNAL.PONE.0127239
Angela Bik-Yu Hui, Kwok-Wai Lo, Sing-Fai Leung, Peter Teo, Michael K.F. Fung, K.F. To, Nathalie Wong, Peter H.K. Choi, Joseph C.K. Lee, Dolly P. Huang, Detection of recurrent chromosomal gains and losses in primary nasopharyngeal carcinoma by comparative genomic hybridisation. International Journal of Cancer. ,vol. 82, pp. 498- 503 ,(1999) , 10.1002/(SICI)1097-0215(19990812)82:4<498::AID-IJC5>3.0.CO;2-S
W H Shuen, R Kan, Z Yu, H L Lung, M L Lung, Novel lentiviral-inducible transgene expression systems and versatile single-plasmid reporters for in vitro and in vivo cancer biology studies. Cancer Gene Therapy. ,vol. 22, pp. 207- 214 ,(2015) , 10.1038/CGT.2015.9
Neil R Cooper, Bonnie M Bradt, Johng S Rhim, Glen R Nemerow, None, CR2 Complement Receptor Journal of Investigative Dermatology. ,vol. 94, pp. s112- s117 ,(1990) , 10.1111/1523-1747.EP12876069
Audrey Petitjean, Ewy Mathe, Shunsuke Kato, Chikashi Ishioka, Sean V. Tavtigian, Pierre Hainaut, Magali Olivier, Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Human Mutation. ,vol. 28, pp. 622- 629 ,(2007) , 10.1002/HUMU.20495