Testing beyond ethnomedical claims: Brine shrimp lethality of some Tanzanian plants

摘要: Extracts of 34 plants that are traditionally used for the treatment different diseases exhibited various degrees toxicity on brine shrimp. The concentration killing 50% (LC50) shrimps was below 50 μg/ml 14 (41.2%), 50–100 μ g/ml 10 (29.4%), and greater than 100 (29.4%) plants, respectively. Dalbergia nitidula (LC50 0.87 μg/ml), Ozoroa insignis 2.21 Markhamia obtusifolia 8.94 Ximenia caffra 11.25 μg/ml),Croton macrostachys 13.40 Mormodica calantha 19.38 μg/ml) were most toxic. results indicate possibility some plant extracts may be toxic or contain useful cytotoxic compounds, which not reported by traditional healers.