Method for determining an allele profile of nucleic acid

作者: Michael Seul

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摘要: A method of identifying alleles polymorphic sites in a plurality nucleic acid samples including the steps determining source tag sharing number “d” for each alleles; performing first reaction pools to be identified produce products said pool; pooling provide pooled pools; identified, second using allele-specific comprising marker and derived tag; identify alleles. If is equal or larger than maximum pool size, may not performed. Alleles binned together. microparticle one more capture probes an oligonucleotide complementary subsequence target polynucleotide.

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