Foam-like scaffolds for bone tissue engineering based on a novel couple of silicate-phosphate specular glasses: synthesis and properties

作者: Chiara Vitale-Brovarone , Francesco Baino , Oana Bretcanu , Enrica Verné

DOI: 10.1007/S10856-009-3788-Z

关键词:

摘要: Glass–ceramic scaffolds mimicking the structure of cancellous bone were produced via sponge replication technique by using a polyurethane foam as template and glass powder below 30 μm inorganic phase. Specifically, SiO2-based complex composition its corresponding P2O5-based “specular” used materials for scaffolding. The polymeric was thermally removed powders sintered to obtain replica structure. investigated compared from structural, morphological mechanical viewpoint assessing their crystalline phases, volumetric shrinkage, pores content interconnection, strength. In addition, soaked in acellular simulated body fluid investigate vitro behaviour. have great potential reconstructive surgery because features, such shape, strength, bioactivity bioresorption, can be easily tailored according end use.

参考文章(37)
Larry L Hench, June Wilson, An Introduction to bioceramics WORLD SCIENTIFIC. ,(1993) , 10.1142/2028
R. Z. LeGeros, S. Lin, R. Rohanizadeh, D. Mijares, J. P. LeGeros, Biphasic calcium phosphate bioceramics: preparation, properties and applications. Journal of Materials Science: Materials in Medicine. ,vol. 14, pp. 201- 209 ,(2003) , 10.1023/A:1022872421333
Naoto Ozawa, Shigeharu Negami, Toshirou Odaka, Takamichi Morii, Tomihisa Koshino, Histological observations on tissue reaction of the rat calcaneal tendon to sintered hydroxyapatite Journal of Materials Science Letters. ,vol. 8, pp. 869- 871 ,(1989) , 10.1007/BF01729929
I Hvid, N C Jensen, C Bünger, K Sølund, J C Djurhuus, Bone Mineral Assay: Its Relation to the Mechanical Strength of Cancellous Bone Engineering in Medicine. ,vol. 14, pp. 79- 83 ,(1985) , 10.1243/EMED_JOUR_1985_014_016_02
Robert C. Thomson, Michael J. Yaszemski, John M. Powers, Antonios G. Mikos, Hydroxyapatite fiber reinforced poly(α-hydroxy ester) foams for bone regeneration Biomaterials. ,vol. 19, pp. 1935- 1943 ,(1998) , 10.1016/S0142-9612(98)00097-0
Wolfgang Schlickewei, Carsten Schlickewei, The Use of Bone Substitutes in the Treatment of Bone Defects – the Clinical View and History Macromolecular Symposia. ,vol. 253, pp. 10- 23 ,(2007) , 10.1002/MASY.200750702
Chiara Vitale-Brovarone, Francesco Baino, Enrica Verné, High strength bioactive glass-ceramic scaffolds for bone regeneration Journal of Materials Science: Materials in Medicine. ,vol. 20, pp. 643- 653 ,(2009) , 10.1007/S10856-008-3605-0
A. S. Rizkalla, D. W. Jones, D. B. Clarke, G. C. Hall, Crystallization of experimental bioactive glass compositions Journal of Biomedical Materials Research. ,vol. 32, pp. 119- 124 ,(1996) , 10.1002/(SICI)1097-4636(199609)32:1<119::AID-JBM14>3.0.CO;2-H
Qizhi Z. Chen, Ian D. Thompson, Aldo R. Boccaccini, 45S5 Bioglass-derived glass-ceramic scaffolds for bone tissue engineering. Biomaterials. ,vol. 27, pp. 2414- 2425 ,(2006) , 10.1016/J.BIOMATERIALS.2005.11.025
Larry L. Hench, Bioactive materials: The potential for tissue regeneration Journal of Biomedical Materials Research. ,vol. 41, pp. 511- 518 ,(1998) , 10.1002/(SICI)1097-4636(19980915)41:4<511::AID-JBM1>3.0.CO;2-F