Computed tomography in untreated adults with virilising congenital adrenal cortical hyperplasia

摘要: Thirteen adult patients with biochemically proven congenital adrenal hyperplasia (CAH) were examined by computed tomography (CT). Six had never received glucocorticoid therapy. In three of those six patients, CT revealed a tumorous transformation in one the hyperplastic glands. seven CAH who treated since childhood, no mass could be demonstrated on CT. The development an adrenocortical tumour due to chronic cortical stimulation excessive adreno-cortico-trophic hormone (ACTH) production untreated may not rare occurrence, as is this series. It important confuse entity primary virilising which requires different form treatment. case adults CAH, suppressive therapy control should favoured over surgery, long ACTH-dependent. Moreover, these observations illustrate desirability life-long including males require suppression steroid androgen excess.