IgA deficiency in children. Immunoglobulin-containing cells in the intestinal mucosa, immunoglobulins in secretions and serum IgA levels.
作者： E Savilahti
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摘要: Twenty-eight children with IgA deficiency were investigated by studying immunoglobulin-containing cells in the jejunal and rectal mucosa direct immunofluorescence measuring immunoglobulins intestinal juice saliva. Serum was measured radioactive single radial immunodiffusion. IgM-containing predominant all biopsy specimens. Their number not altered three coeliac patients. The of IgG-containing elevated jejunal, but mucosa. IgE-containing altered. Staining structures anti-IgM serum had same characteristics as observed anti-IgA normal children. IgM predominated juice. salivary content higher than controls, it surpassed IgG. Traces detected sera eighteen Most these a few IgA-containing some secretions. The study indicates that deficient is quantitatively replaced intestine deficiency. IgA-deficient has common
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