Ultrasound-assisted low-density solvent dispersive liquid-liquid extraction for the determination of alkanolamines and alkylamines in cosmetics with ion chromatography.

摘要: Abstract A new one-step sample preparation technique termed ultrasound-assisted low-density solvent dispersive liquid–liquid extraction (UA-LDS-DLLE) coupled with ion chromatography (IC) was developed for the determination of three alkanolamines and two alkylamines in complex samples. Sample matrices were rapidly dissolved dispersed to form cloudy solutions by using solvents, where target analytes transferred into acid solutions, while liposoluble substances cyclohexane. The obtained extracts could be used directly injection analysis without any additional purification because potential matrix interferences had been effectively eliminated process. efficiency markedly enhanced quickly accomplished within 13 min under synergistic effects ultrasound radiation, vibration heating. Various parameters influencing evaluated orthogonal array experimental design. performance approach demonstrated 15 commercial cosmetics covering very different matrices. Linearity ranges 0.3–50 mg L −1 limits detection varying from 0.072 0.12 mg L achieved. recoveries ranged 86.9–108.5% relative standard deviations (RSDs) 1.2–6.2%. method proved a simple effective that provided an attractive alternative trace amounts large numbers cosmetics.