CONTRIBUTION OF TOXICOLOGICAL ANALYSIS TO THE CARE OF DIMETHYL FUMARATE DERMATITIS
作者： L. Lagarce , M. Avenel-Audran , M. Bretaudeau , G. Leboulanger , B. Lelièvre
DOI: 10.1179/ACB.2010.114
关键词:
摘要: AbstractBackground: Dimethyl fumarate (DMFu) is a fungicide which used in Chinese manufactures of furniture and shoes to avoid mould spoiling fabrics. In 2008, DMFu was found the responsible allergen for several cases contact dermatitis from armchairs observed Europe. France national toxicovigilance survey set up importation products containing dimethyl now forbidden.Case report: 36 year-old woman, with no history previous allergy, hospitalized because severe acute eczema her feet after wearing new pair boots inside she had noticed desiccant sachets. She strongly reacted on patch testing content sachet identified as DMFu, both at 0.01%, 0.1%, 1% petrolatum, also piece fabric boots, tested is.Materials method: boot fabrics mould-proof sachets were analysed by HPLC/UV/DAD GC/MS methanol extraction. Further samples anti moul...
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