Therapeutic benefits from nanoparticles: the potential significance of nanoscience in diseases with compromise to the blood brain barrier.

作者: Silke Krol , Richard Macrez , Fabian Docagne , Gilles Defer , Sophie Laurent

DOI: 10.1021/CR200472G

关键词:

摘要: … brain AQP4 could be developed as putative therapeutic tools in brain edema and other brain diseases… For example, inhibitors of AQP4 are predicted to reduce brain swelling in cytotoxic …

参考文章(388)
Xu, Gu Julin, Zhu Yuanjie, Wen Hai, Ren Qiushi, Chen Jianghan, Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice International Journal of Nanomedicine. ,vol. 6, pp. 905- 913 ,(2011) , 10.2147/IJN.S17503
Nobuhisa Iwata, Satoshi Tsubuki, Emi Hama, Yoshie Takaki, Keiro Shirotani, Takaomi C. Saido, Reply to: 'Clearance of amyloid β-peptide from brain: transport or metabolism?' Nature Medicine. ,vol. 6, pp. 718- 719 ,(2000) , 10.1038/77399
H Grasberger, P Jung, J Vlotides, O E Janssen, R Landgraf, S Hofmann, M Bidlingmaier, The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expression. European Journal of Medical Research. ,vol. 7, pp. 171- 176 ,(2002)
Lawrence K. Fung, Marian Shin, Betty Tyler, Henry Brem, W. Mark Saltzman, Chemotherapeutic drugs released from polymers : Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain Pharmaceutical Research. ,vol. 13, pp. 671- 682 ,(1996) , 10.1023/A:1016083113123
Sònia Solé, Valérie Petegnief, Roser Gorina, Ángel Chamorro, Anna M. Planas, Activation of matrix metalloproteinase-3 and agrin cleavage in cerebral ischemia/reperfusion. Journal of Neuropathology and Experimental Neurology. ,vol. 63, pp. 338- 349 ,(2004) , 10.1093/JNEN/63.4.338
Regina C. Reszka, Andreas Jacobs, Jürgen Voges, Liposome-mediated suicide gene therapy in humans Methods in Enzymology. ,vol. 391, pp. 200- 208 ,(2005) , 10.1016/S0076-6879(05)91012-4
Alexander E. Gulyaev, Svetlana E. Gelperina, Igor N. Skidan, Arkady S. Antropov, Gregory Ya. Kivman, Jörg Kreuter, Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles Pharmaceutical Research. ,vol. 16, pp. 1564- 1569 ,(1999) , 10.1023/A:1018983904537
Olivier Nicole, Fabian Docagne, Carine Ali, Isabelle Margaill, Peter Carmeliet, Eric T. MacKenzie, Denis Vivien, Alain Buisson, The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nature Medicine. ,vol. 7, pp. 59- 64 ,(2001) , 10.1038/83358
Robert E. Becker, Nigel H. Greig, Ezio Giacobini, Why do so many drugs for Alzheimer's disease fail in development? Time for new methods and new practices? Journal of Alzheimer's Disease. ,vol. 15, pp. 303- 325 ,(2008) , 10.3233/JAD-2008-15213