The Mechanics of Morphogenesis in Multicellular Embryos

摘要: Our subject is morphogenesis, the shaping of a multicellular embryo. As an embryo develops, it acquires sequentially characteristic levels biological organization: A single cell, fertilized egg, generates mass cells which form tissues, then organs, organ systems. Processes at all these depend on each other; to understand morphogenesis one must unravel this interdependence. The major current investigations in cell biomechanics relation between activities and molecular processes that mediate activities. In most experiments focus behavior cells, or interactions pairs cells. However, such studies leave unresolved many-cell problem: How do many interacting diverse ways, shape embryo?